Article
Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies.
Journal of clinical microbiology - 1 Feb 2006
Laperche Syria, Saune Karine, Dény Paul, Duverlie Gilles, Alain Sophie, Chaix Marie-Laure, Gaudy Catherine, Lunel Françoise, Pawlotsky Jean-Michel, Payan Christopher, Pozzetto Bruno, Tamalet Catherine, Thibault Vincent, Vallet Sophie, Bouchardeau Françoise, Izopet Jacques, Lefrère Jean-Jacques
Abstract excerpt
A multicenter study of NS5b hepatitis C virus (HCV) genotype determination involving 12 laboratories demonstrates that any laboratory with expertise in sequencing techniques would be able to provide a reliable HCV genotype for clinical and epidemiological purposes as long as they are provided a consensus reference sequence database.
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