Article
Application of a rank-based genetic association test to age-at-onset data from the Collaborative Study on the Genetics of Alcoholism study.
BMC genetics - 30 Dec 2005
Li Yi-Ju, Martin Eden R, Zhang Ling, Allen Andrew S
Abstract excerpt
Association studies of quantitative traits have often relied on methods in which a normal distribution of the trait is assumed. However, quantitative phenotypes from complex human diseases are often censored, highly skewed, or contaminated with outlying values. We recently developed a rank-based association method that takes into account censoring and makes no distributional assumptions about the trait. In this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
