Article
Use of susceptibility scoring in conjunction with the genotypic transmission disequilibrium test.
BMC genetics - 30 Dec 2005
Benke Kelly S, Chase Gary A, Fallin Daniele M
Abstract excerpt
We explored the utility of selecting a genetically predisposed subgroup to increase the finding of a genetic signal in the Genetic Analysis Workshop 14 Collaborative Study on the Genetics of Alcoholism dataset. A subgroup of affected probands with low environmental risk exposures was defined using a susceptibility score calculated from an environmental risk model. Thirty-nine probands with highly positive scores...
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