Article
Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in Native Americans and whites in the Hemochromatosis and Iron Overload Screening Study.
Clinical genetics - 1 Jan 2006
Barton J C, Acton R T, Lovato L, Speechley M R, McLaren C E, Harris E L, Reboussin D M, Adams P C, Dawkins F W, Gordeuk V R, Walker A P
Abstract excerpt
We compared initial screening transferrin saturation (TfSat) and serum ferritin (SF) phenotypes and HFE C282Y and H63D genotypes of 645 Native American and 43,453 white Hemochromatosis and Iron Overload Screening Study participants who did not report a previous diagnosis of hemochromatosis or iron overload. Elevated measurements were defined as TfSat >50% in men and >45% in women and SF >300 ng/ml in men and >200...
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