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Article

HFE genotype and transferrin saturation in the United States.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Cogswell Mary E, Gallagher Margaret L, Steinberg Karen K, Caudill PhD Samuel P, Looker Anne C, Bowman Barbara A, Gunter Elaine W, Franks Adele L, Satten Glen A, Khoury Muin J, Grummer-Strawn Laurence M

Abstract excerpt

PURPOSE: Examine the penetrance (defined by high transferrin saturation [TS]) of C282Y and H63D in the U.S. population. METHODS: 5171 participants from the Third National Health and Nutrition Examination Survey, 1992 to 1994. RESULTS: 77.1% (95% confidence interval [CI], 2.3, 95.1) of men and 51.9% (95% CI, 0, 84.2) of women with C282Y homozygosity had high TS. The associations of H63D homozygosity with high TS...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12865759
DOI: 10.1097/01.GIM.0000076976.08421.AB

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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