Article
Affinity capillary electrophoresis with a DNA-nanoparticle conjugate as a new tool for genotyping.
Journal of chromatography. A - 24 Mar 2006
Adachi Ken, Noda Naohiro, Nakashige Makoto, Tsuneda Satoshi, Kanagawa Takahiro
Abstract excerpt
We have developed a novel method for genotyping based on free solution affinity capillary electrophoresis. We prepared DNA-nanoparticle conjugates by mixing biotin-modified DNA and NeutrAvidin-modified polystyrene nanoparticles; this mixture was then injected into a capillary. Subsequently, we injected the fluorescent-labeled sample DNAs into the capillary, applied the voltage, increased its temperature after 7...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
