Article
Genetic dissection of cyclophilin function. Saturation mutagenesis of the Drosophila cyclophilin homolog ninaA.
The Journal of biological chemistry - 15 Aug 1992
Ondek B, Hardy R W, Baker E K, Stamnes M A, Shieh B H, Zuker C S
Abstract excerpt
Cyclophilins, the intracellular receptors for the widely used immunosuppressant cyclosporin A have been found to be peptidyl-prolyl cis/trans isomerases and have been implicated in intracellular protein folding and trafficking. The Drosophila ninaA gene encodes a photoreceptor-specific cyclophili...
Topics
- Alleles
- Amino Acid Isomerases
- Amino Acid Sequence
- Animals
- Base Sequence
- Carrier Proteins
- Cyclosporins
- Drosophila
- Drosophila Proteins
- Ethyl Methanesulfonate
- Humans
- Insect Hormones
- Kinetics
- Male
- Membrane Proteins
- Models, Molecular
- Molecular Chaperones
- Molecular Sequence Data