Article
[Association between genetic polymorphisms in methylentetrahydrofolate reductase and risk of lung cancer].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Dec 2005
Zhang Xue-mei, Miao Xiao-ping, Tan Wen, Qu Shi-ning, Sun Tong, Zhou Yi-feng, Lin Dong-xin
Abstract excerpt
OBJECTIVE: To investigate the association between methylentetrahydrofolate reductase (MTHFR) polymorphisms and risk of lung cancer. METHODS: Totally 505 cases with lung cancer and 500 frequency-matched controls were genotyped for the MTHFR C677T and A1298C polymorphisms by polymerase chain reacti...
Topics
- Adult
- Aged
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Lung Neoplasms
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Polymorphism, Genetic
- Risk