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Article

Expansion and redifferentiation of adult human pancreatic islet cells.

Biochemical and biophysical research communications - 10 Mar 2006

Ouziel-Yahalom Limor, Zalzman Michal, Anker-Kitai Leeat, Knoller Sarah, Bar Yael, Glandt Mariela, Herold Kevan, Efrat Shimon

Abstract excerpt

Beta-cell replacement represents the ultimate cure for type 1 diabetes, however it is limited by availability of organ donors. Adult human islets are difficult to propagate in culture, and efforts to expand them result in dedifferentiation. Here we describe conditions for expansion of adult human islet cells, as well as a way for their redifferentiation. Most cells in islets isolated from human pancreata were...

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Identifiers

PMID: 16446152
DOI: 10.1016/j.bbrc.2005.12.187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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