Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data.

doi:10.1093/genetics/131.2.479

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Article

Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data.

Genetics - 1 Jun 1992

Excoffier L, Smouse P E, Quattro J M

Abstract excerpt

We present here a framework for the study of molecular variation within a single species. Information on DNA haplotype divergence is incorporated into an analysis of variance format, derived from a matrix of squared-distances among all pairs of haplotypes. This analysis of molecular variance (AMO...

Topics

Analysis of Variance
DNA, Mitochondrial
Ethnicity
Gene Frequency
Genetic Variation
Haplotypes
Humans
Models, Genetic
Restriction Mapping

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