Article
The structure of human mitochondrial DNA variation.
Journal of molecular evolution - 1 Dec 1991
Merriwether D A, Clark A G, Ballinger S W, Schurr T G, Soodyall H, Jenkins T, Sherry S T, Wallace D C
Abstract excerpt
Restriction analysis of mitochondrial DNA (mtDNA) of 3065 humans from 62 geographic samples identified 149 haplotypes and 81 polymorphic sites. These data were used to test several aspects of the evolutionary past of the human species. A dendrogram depicting the genetic relatedness of all haplotypes shows that the native African populations have the greatest diversity and, consistent with evidence from a variety...
Topics
- Alleles
- DNA, Mitochondrial
- Genetic Variation
- Humans
- Linkage Disequilibrium
- Polymorphism, Restriction Fragment Length
- Racial Groups