A genetic marker at the glucokinase gene locus for type 2 (non-insulin-dependent) diabetes mellitus in Mauritian Creoles.

doi:10.1007/BF00400254

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Article

A genetic marker at the glucokinase gene locus for type 2 (non-insulin-dependent) diabetes mellitus in Mauritian Creoles.

Diabetologia - 1 Jul 1992

Chiu K C, Province M A, Dowse G K, Zimmet P Z, Wagner G, Serjeantson S, Permutt M A

Abstract excerpt

The prevalence of Type 2 (non-insulin-dependent) diabetes mellitus is high in Mauritius, a multiethnic island nation in the southwestern Indian Ocean. Evaluation of candidate genes in the different ethnic groups represents a means of assessing the genetic component. As glucokinase is known to be a key regulator of glucose homeostasis in liver and pancreatic Beta-cells, the human gene was isolated and a...

Topics

Africa
Age Factors
Alleles
Analysis of Variance
Base Sequence
Diabetes Mellitus, Type 2
Ethnicity
Europe
Female
Gene Frequency
Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Glucokinase

HLA-DR Antigens

Histocompatibility Testing

Humans

India

Madagascar

Source

Open in PubMed

Identifiers

PMID: 1644240
DOI: 10.1007/BF00400254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1644240-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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