Article
Early-onset type 2 (non-insulin-dependent) diabetes mellitus is associated with glucokinase locus, but not with adenosine deaminase locus, in the Japanese population.
Diabetes research and clinical practice - 1 Apr 1994
Takekawa K, Ikegami H, Fukuda M, Ueda H, Kawaguchi Y, Fujioka Y, Fujisawa T, Ogihara T
Abstract excerpt
To investigate the possible contribution of glucokinase (GCK) and adenosine deaminase (ADA) loci to the genetic susceptibility to type 2 (non-insulin-dependent) diabetes mellitus, we studied the association of these loci with type 2 diabetes in the Japanese population. Fifty patients with type 2...
Topics
- Adenosine Deaminase
- Adult
- Age Factors
- Alleles
- Base Sequence
- Chromosome Mapping
- DNA Primers
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genetic Linkage
- Genotype
- Glucokinase
- Humans
- Japan