Article
Early-onset type 2 (non-insulin-dependent) diabetes mellitus is associated with glucokinase locus, but not with adenosine deaminase locus, in the Japanese population.
Diabetes research and clinical practice - 1 Apr 1994
Takekawa K, Ikegami H, Fukuda M, Ueda H, Kawaguchi Y, Fujioka Y, Fujisawa T, Ogihara T
Abstract excerpt
To investigate the possible contribution of glucokinase (GCK) and adenosine deaminase (ADA) loci to the genetic susceptibility to type 2 (non-insulin-dependent) diabetes mellitus, we studied the association of these loci with type 2 diabetes in the Japanese population. Fifty patients with type 2 diabetes and 50 control subjects were analyzed for microsatellite polymorphism 3' to the GCK gene and PstI polymorphism...
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