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Article

A likelihood ratio approach to family-based association studies with covariates.

Annals of human genetics - 1 Jan 2006

Baksh M F, Balding D J, Vyse T J, Whittaker J C

Abstract excerpt

We introduce a procedure for association based analysis of nuclear families that allows for dichotomous and more general measurements of phenotype and inclusion of covariate information. Standard generalized linear models are used to relate phenotype and its predictors. Our test procedure, based on the likelihood ratio, unifies the estimation of all parameters through the likelihood itself and yields maximum...

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Source

Identifiers

PMID: 16441262
DOI: 10.1111/j.1529-8817.2005.00189.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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