Article
Circadian Clock mutation in dams disrupts nursing behavior and growth of pups.
Endocrinology - 1 Apr 2006
Hoshino Kyoko, Wakatsuki Yukako, Iigo Masayuki, Shibata Shigenobu
Abstract excerpt
To understand the role of the circadian molecular clock in mouse reproduction, we investigated the daily rhythms associated with nursing and pup growth in Clock-mutant mice maintained under light-dark housing conditions. The daily rhythm associated with the maternal behavior of crouching had a strong diurnal peak and two weak nocturnal peaks in wild-type dams, whereas homozygotes (Clock/Clock) exhibited no...
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