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Article

Variable severity of pulmonary disease in adults with identical cystic fibrosis mutations.

Chest - 1 Aug 1992

Burke W, Aitken M L, Chen S H, Scott C R

Abstract excerpt

Adults with CF followed in a university center were assessed for the presence of the most common CF gene mutation, delta-F508. Excluding one member of a sibling pair, 29 of 55 subjects had two copies of delta-F508 (homozygotes), 23 had one copy of delta-F508 with the other CF mutation not identified (complex heterozygotes) and three were lacking delta-F508. A wide range of clinical severity was seen among...

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Identifiers

PMID: 1643940
DOI: 10.1378/chest.102.2.506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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