Delta F508 genotype does not predict disease severity in an ethnically diverse cystic fibrosis population.

Article

Delta F508 genotype does not predict disease severity in an ethnically diverse cystic fibrosis population.

Pediatrics - 1 Jan 1994

Lester L A, Kraut J, Lloyd-Still J, Karrison T, Mott C, Billstrand C, Lemke A, Ober C

Abstract excerpt

OBJECTIVE: As part of a study to determine population-based frequencies of CFTR mutations in an ethnically diverse, midwestern cystic fibrosis (CF) population, clinical histories were studied in 119 CF patients. METHODOLOGY: We sought to examine the association between genotype as characterized b...

Topics

Adolescent
Child
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Female
Forced Expiratory Volume
Genotype
Homozygote
Humans
Male
Membrane Proteins
Mutation
Prognosis

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