Article
Analysis of the delta F508 mutation in a Brazilian cystic fibrosis population: comparison of pulmonary status of homozygotes with other patients.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Apr 1998
Maróstica P J, Raskin S, Abreu-e-Silva F A
Abstract excerpt
Sixty-one cystic fibrosis patients admitted for check-up or antibiotic treatment were enrolled for genetic and clinical evaluation. Genetic analysis was performed on blood samples stored on neonatal screening cards using PCR techniques to determine the presence of delta F508 mutations. Clinical e...
Topics
- Adolescent
- Brazil
- Child
- Child, Preschool
- Cross-Sectional Studies
- Cystic Fibrosis
- Female
- Homozygote
- Humans
- Infant
- Logistic Models
- Lung
- Male
- Mutation
- Odds Ratio
- Phenylalanine
- Respiratory Function Tests