Article
A genetic screen for behavioral mutations that perturb dopaminergic homeostasis in mice.
Genes, brain, and behavior - 1 Feb 2006
Speca D J, Rabbee N, Chihara D, Speed T P, Peterson A S
Abstract excerpt
Disruption of dopaminergic (DA) systems is thought to play a central role in the addictive process and in the pathophysiology of schizophrenia. Although inheritance plays an important role in the predisposition to these disorders, the genetic basis of this is not well understood. To provide additional insight, we have performed a modifier screen in mice designed to identify mutations that perturb DA homeostasis....
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