Article
Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development.
Developmental biology - 15 Mar 2006
St Amand Tara R, Lu Jonathan T, Zamora Monica, Gu Yusu, Stricker Janelle, Hoshijima Masahiko, Epstein Jonathan A, Ross John J, Ruiz-Lozano Pilar, Chien Kenneth R
Abstract excerpt
The heterogeneous cell types of the cardiac conduction system are responsible for coordinating and maintaining rhythmic contractions of the heart. While it has been shown that the cells of the conduction system are derived from myocytes, additional cell types, including neural crest cells, may play a role in the development and maturation of these specialized cell lineages. Previous work has shown that the...
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