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Article

Regulation of the Glucosyltransferase ( gtfBC ) Operon by CovR in Streptococcus mutans

20 Jan 2006

Abstract excerpt

Streptococcus mutans is an important etiological agent of dental caries in humans. The extracellular polysaccharides synthesized by cell-associated glucosyltransferases (encoded by gtfBC) from sucrose have been recognized as one of the important virulence factors that promote cell aggregation and adherence to teeth, leading to dental plaque formation. In this study, we have characterized the effect of CovR, a...

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Identifiers

PMID: 16428403
DOI: 10.1128/jb.188.3.988-998.2006

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