Article
Molecular and biological characterization of gtf regulation-associated genes in Streptococcus mutans.
Oral microbiology and immunology - 1 Jun 2009
Terao Y, Isoda R, Murakami J, Hamada S, Kawabata S
Abstract excerpt
INTRODUCTION: Surface protein antigen (PAc) and glucosyltransferases (GTF) are major adhesive molecules of Streptococcus mutans, though the mechanism of their regulation has not been fully elucidated. METHODS: To investigate the regulation mechanism, we determined a nucleotide sequence in the upstream region of the pac locus in S. mutans and identified two open reading frames (ORF), designated as orf1 and orf2....
Topics
- Antigens, Bacterial
- Bacterial Adhesion
- Bacterial Proteins
- Blotting, Western
- Down-Regulation
- Electrophoresis, Polyacrylamide Gel
- Gene Expression Regulation, Enzymologic
- Glucans
- Glucosyltransferases
- Humans
- Hydrophobic and Hydrophilic Interactions
- Immunoblotting
- Membrane Proteins