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Article

DNA sequence analysis of rdxA and frxA from paired metronidazole-sensitive and -resistant Helicobacter pylori isolates obtained from patients with heteroresistance.

International journal of antimicrobial agents - 1 Feb 2006

Matteo Mario José, Pérez Cecilia Valeria, Domingo Mara Roxana, Olmos Martín, Sanchez Cristian, Catalano Mariana

Abstract excerpt

Genomic variations of rdxA and frxA genes in eight pairs of metronidazole (MTZ)-sensitive and -resistant isolates of Helicobacter pylori were investigated. The paired strains from each single biopsy had identical lspA-glmM restriction fragment length polymorphism profiles, and the differences in MTZ susceptibility were mostly accounted for by mutations in the rdxA gene. Truncation of RdxA is associated with a...

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Identifiers

PMID: 16426819
DOI: 10.1016/j.ijantimicag.2005.09.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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