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Article

The different roles of aggrecan interaction domains.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Dec 2012

Aspberg Anders

Abstract excerpt

The aggregating proteoglycans of the lectican family are important components of extracellular matrices. Aggrecan is the most well studied of these and is central to cartilage biomechanical properties and skeletal development. Key to its biological function is the fixed charge of the many glycosaminoglycan chains, that provide the basis for the viscoelastic properties necessary for load distribution over the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23019016
DOI: 10.1369/0022155412464376
PMCID: PMC3527881

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