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Directed evolution of RuBisCO hypermorphs through genetic selection in engineered E.coli.

Protein engineering, design & selection : PEDS - 1 Mar 2006

Parikh Monal R, Greene Dina N, Woods Kristen K, Matsumura Ichiro

Abstract excerpt

The Calvin Cycle is the primary conduit for the fixation of carbon dioxide into the biosphere; ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO) catalyzes the rate-limiting fixation step. Our goal is to direct the evolution of RuBisCO variants with improved kinetic and biophysical properties. The Calvin Cycle was partially reconstructed in Escherichia coli; the engineered strain requires the Synechococcus...

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Source

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Identifiers

PMID: 16423843
DOI: 10.1093/protein/gzj010
PMCID: PMC2012944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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