Article
Osmolyte-induced transcription: -35 region elements and recognition by sigma38 (rpoS).
Molecular microbiology - 1 Feb 2006
Rosenthal Adam Z, Hu Minshan, Gralla Jay D
Abstract excerpt
In order to meet osmotic challenges in the gastrointestinal tract, enteric bacteria rapidly accumulate salts of glutamate and other weak organic acids. The ensuing transcriptional activation is mediated by unknown elements at sigma38 (rpoS)-dependent promoters. Here we identify DNA elements needed for high levels of transcription in the presence of salt and acetate and show that they are associated with the -35...
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