Insight on the roles of stringent response, stringent-like response, and general stress response in hyperosmotic shock tolerance in Escherichia coli.

Abstract excerpt

Bacteria frequently encounter osmotic stress in a variety of natural environments, and the primary protective systems they use to adapt to such stresses have been well-characterized. The work examining these mechanisms has largely focused on their role in adapting to moderate shock or continuous osmotic stress. However, survival of rapid, severe osmotic stress remains poorly understood. Here, we demonstrate that...

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