Article
Significance of hepatitis B virus genotypes A to E in a cohort of patients with chronic hepatitis B in the Seine Saint Denis District of Paris (France).
Journal of medical virology - 1 Mar 2006
Ganne-Carrié Nathalie, Williams Virginie, Kaddouri Halima, Trinchet Jean-Claude, Dziri-Mendil Samira, Alloui Chakib, Hawajri Nasser Al, Dény Paul, Beaugrand Michel, Gordien Emmanuel
Abstract excerpt
The aim of this study was to examine the genetic variability of the hepatitis B virus (HBV) and its significance. HBV genotypes, core promoter and precore mutants were characterized in 109 consecutive patients with biopsy-proven HBV chronic hepatitis. Genotypes A (26.6%), B (12.8%), C (18.3%), D (18.3%), and E (14.7%) indicate a wide genotypic distribution. Patients were from Asia (30.3%), Europe (28.4%), Sub...
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