Article
An SNP in the adiponectin gene is associated with decreased serum adiponectin levels and risk for impaired glucose tolerance.
Obesity research - 1 May 2005
González-Sánchez José L, Zabena Carina A, Martínez-Larrad María T, Fernández-Pérez Cristina, Pérez-Barba Milagros, Laakso Markku, Serrano-Ríos Manuel
Abstract excerpt
Adiponectin is a plasma protein produced by the adipose tissue. Hypoadiponectinemia has been associated with insulin resistance and several components of the metabolic syndrome (MS): type 2 diabetes, obesity, and dyslipidemia. We investigated whether single nucleotide polymorphisms (SNPs) at positions 45 and 276 in the adiponectin gene were associated with features of the MS in 747 unrelated Spanish subjects. The...
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