Article
Cancer as an emergent phenomenon in systems radiation biology.
Radiation and environmental biophysics - 1 Feb 2008
Barcellos-Hoff Mary Helen
Abstract excerpt
Radiation-induced DNA damage elicits dramatic cell signaling transitions, some of which are directed towards deciding the fate of that particular cell, while others lead to signaling to other cells. Each irradiated cell type and tissue has a characteristic pattern of radiation-induced gene expression, distinct from that of the unirradiated tissue and different from that of other irradiated tissues. It is the sum...
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