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Article

Increased risk for treatment-related mortality after bone marrow transplantation in GSTM1-positive recipients.

Bone marrow transplantation - 1 Feb 2006

Terakura S, Murata M, Nishida T, Emi N, Akatsuka Y, Morishima Y, Kodera Y, Naoe T

Abstract excerpt

Treatment-related mortality (TRM) is a major obstacle to successful allogeneic hematopoietic stem cell transplantation (HSCT). A variety of drugs are used in allogeneic HSCT, and a genetic polymorphism in metabolic enzymes could affect the metabolism of drugs and potentially influence TRM. Here, we focused attention on GSTM1 and GSTT1 enzymes, which metabolize chemotherapeutic agents, chemical carcinogens and...

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Source

Identifiers

PMID: 16415899
DOI: 10.1038/sj.bmt.1705257

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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