Article
Increased risk for treatment-related mortality after bone marrow transplantation in GSTM1-positive recipients.
Bone marrow transplantation - 1 Feb 2006
Terakura S, Murata M, Nishida T, Emi N, Akatsuka Y, Morishima Y, Kodera Y, Naoe T
Abstract excerpt
Treatment-related mortality (TRM) is a major obstacle to successful allogeneic hematopoietic stem cell transplantation (HSCT). A variety of drugs are used in allogeneic HSCT, and a genetic polymorphism in metabolic enzymes could affect the metabolism of drugs and potentially influence TRM. Here,...
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