Article
Genetics of risk factors for graft-versus-host disease.
Seminars in hematology - 1 Jan 2006
Petersdorf Effie W, Malkki Mari
Abstract excerpt
Modern understanding of the genetic basis of graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplantation (HSCT) involves knowledge of human leukocyte antigen (HLA), killer immunoglobulin-like receptors (KIR), cytokine genes, and their interactions. Insights into the immunogenetic basis of GVHD come from long-standing clinical experience in the use of myeloablative conditioning regimens...
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