Article
Analysis of the human cytomegalovirus genomic region from UL146 through UL147A reveals sequence hypervariability, genotypic stability, and overlapping transcripts.
Virology journal - 12 Jan 2006
Lurain Nell S, Fox Andrea M, Lichy Heather M, Bhorade Sangeeta M, Ware Carl F, Huang Diana D, Kwan Sau-Ping, Garrity Edward R, Chou Sunwen
Abstract excerpt
BACKGROUND: Although the sequence of the human cytomegalovirus (HCMV) genome is generally conserved among unrelated clinical strains, some open reading frames (ORFs) are highly variable. UL146 and UL147, which encode CXC chemokine homologues are among these variable ORFs. RESULTS: The region of the HCMV genome from UL146 through UL147A was analyzed in clinical strains for sequence variability, genotypic...
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