Article
Human cytomegalovirus-encoded alpha -chemokines exhibit high sequence variability in congenitally infected newborns.
The Journal of infectious diseases - 15 Mar 2006
Arav-Boger Ravit, Foster Charles B, Zong Jian-Chao, Pass Robert F
Abstract excerpt
Most congenital human cytomegalovirus (HCMV) infections are asymptomatic, but some lead to severe disease. We hypothesized that differences in disease manifestations may be partially explained by differences in viral strains. We recently reported an association between unique long (UL) 144 gene polymorphisms and clinical disease. We now report on the sequence heterogeneity of 2 potential HCMV virulence genes that...
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