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Article

Docking studies show that D-glucose and quercetin slide through the transporter GLUT1.

The Journal of biological chemistry - 3 Mar 2006

Cunningham Philip, Afzal-Ahmed Iram, Naftalin Richard J

Abstract excerpt

On a three-dimensional templated model of GLUT1 (Protein Data Bank code 1SUK), a molecular recognition program, AUTODOCK 3, reveals nine hexose-binding clusters spanning the entire "hydrophilic" channel. Five of these cluster sites are within 3-5 A of 10 glucose transporter deficiency syndrome missense mutations. Another three sites are within 8 A of two other missense mutations. D-glucose binds to five sites in...

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Identifiers

PMID: 16407180
DOI: 10.1074/jbc.M509422200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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