Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The T393C polymorphism of the GNAS1 gene is associated with deficit schizophrenia in an Italian population sample.

Neuroscience letters - 1 Jan 2000

Minoretti Piercarlo, Politi Pierluigi, Coen Enrico, Di Vito Clara, Bertona Marco, Bianchi Marika, Emanuele Enzo

Abstract excerpt

Programmed cell death and alterations in intracellular G-protein signaling may be involved in the pathophysiology of schizophrenia. The Galphas subunit of heterotrimeric G-proteins, encoded by the gene GNAS1, may play a role in both of these processes. Additionally, transgenic mice expressing a constitutively active form of Galphas provide a reliable model of certain endophenotypes of schizophrenia. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromogranins
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gs

Share to Psychiatric Status Rating Scales

Share to Schizophrenia

Share to Schizophrenic Psychology

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 16406317
DOI: 10.1016/j.neulet.2005.12.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The T393C polymorphism of the GNAS1 gene is associated with deficit schizophrenia in an Italian population sample.PMID 16406317Read ↗

The PIP5K2A and RGS4 genes are differentially associated with deficit and non-deficit schizophrenia.Semantic proximity Read ↗

Association study of NRG1, DTNBP1, RGS4, G72/G30, and PIP5K2A with schizophrenia and symptom severity in a Hungarian sample.Semantic proximity Read ↗

Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity.Semantic proximity Read ↗

BDNF rs 6265 polymorphism and COMT rs 4680 polymorphism in deficit schizophrenia in Polish sample.Semantic proximity Read ↗

Association of β-Secretase Functional Polymorphism with Risk of Schizophrenia.Semantic proximity Read ↗

A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia.Semantic proximity Read ↗

Functional polymorphism of matrix metalloproteinase-9 (MMP9) gene is not associated with schizophrenia and with its deficit subtype.Semantic proximity Read ↗

Association between a casein kinase 1 ε gene polymorphism and schizophrenia in a Chinese Han population.Semantic proximity Read ↗

The deficit subtype of schizophrenia is associated with a pro-inflammatory phenotype but not with altered levels of zonulin: Findings from a case-control study.Semantic proximity Read ↗

Association of GAD1 gene polymorphism rs3749034 with the information processing and cognitive event-related potentials in schizophrenia patients and healthy subjects.Semantic proximity Read ↗

The CNR1 gene as a pharmacogenetic factor for antipsychotics rather than a susceptibility gene for schizophrenia.Semantic proximity Read ↗

Genetic etiology of schizophrenia: possible role of immunoglobulin γ genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.