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The deficit subtype of schizophrenia is associated with a pro-inflammatory phenotype but not with altered levels of zonulin: Findings from a case-control study.

Psychoneuroendocrinology - 1 Jul 2023

Cyran Agnieszka, Pawlak Edyta, Piotrowski Patryk, Bielawski Tomasz, Samochowiec Jerzy, Tyburski Ernest, Chęć Magdalena, Rembacz Krzysztof, Łaczmański Łukasz, Bieniek Wiktoria, Gamian Andrzej, Misiak Błażej

Abstract excerpt

There is evidence that subclinical inflammation and increased gut permeability might be involved in the pathophysiology of schizophrenia. Less is known about these phenomena in patients with the deficit subtype of schizophrenia (D-SCZ) characterized by primary and enduring negative symptoms. Therefore, in the present study we aimed to compare the levels of zonulin (the marker of gut permeability) and...

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PMID: 37075652
DOI: 10.1016/j.psyneuen.2023.106109

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