Article
Distortion of maternal-fetal angiotensin II type 1 receptor allele transmission in pre-eclampsia.
Journal of medical genetics - 1 Aug 1998
Morgan L, Crawshaw S, Baker P N, Brookfield J F, Broughton Pipkin F, Kalsheker N
Abstract excerpt
OBJECTIVE: To investigate the fetal angiotensin II type 1 receptor genotype in pre-eclampsia. DESIGN: Case-control study. POPULATION: Forty-one maternal-fetal pairs from pre-eclamptic pregnancies and 80 maternal-fetal pairs from normotensive pregnancies. METHODS: Maternal and fetal DNA was genotyped at three diallelic polymorphisms, at nucleotides 573, 1062, and 1166, in the coding exon of the angiotensin II type...
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