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Article

Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance.

Kidney international - 1 Feb 2006

Axelsson J, Bergsten A, Qureshi A R, Heimbürger O, Bárány P, Lönnqvist F, Lindholm B, Nordfors L, Alvestrand A, Stenvinkel P

Abstract excerpt

In the present study, we explore the role of decreased renal function and a genetic polymorphism on the recently discovered protein resistin, apparently able to inhibit hepatic insulin action in mice. We also investigate possible links with inflammation and the insulin resistance present in patients with chronic kidney disease (CKD). This is a post hoc, cross-sectional study comparing 239 prevalent CKD patients...

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Source

Identifiers

PMID: 16395259
DOI: 10.1038/sj.ki.5000089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance.PMID 16395259Read ↗

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Human Resistin Gene: Molecular Scanning and Evaluation of Association with Insulin Sensitivity and Type 2 Diabetes in CaucasiansSemantic proximity Read ↗

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.Semantic proximity Read ↗

Absence of evidence for an association between resistin gene variants and insulin resistance in an Asian population with low and high blood pressure.Semantic proximity Read ↗

Increased expression of pro-inflammatory genes in abdominal subcutaneous fat in advanced chronic kidney disease patientsSemantic proximity Read ↗

A promoter genotype and oxidative stress potentially link resistin to human insulin resistance.Semantic proximity Read ↗

High plasma chemerin is associated with renal dysfunction and predictive for cardiovascular events - Insights from phenotype and genotype characterization.Semantic proximity Read ↗

Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Québec Family Study.Semantic proximity Read ↗

Circulating levels of visfatin/pre-B-cell colony-enhancing factor 1 in relation to genotype, GFR, body composition, and survival in patients with CKD.Semantic proximity Read ↗

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