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Article

Molecular basis of fusB-mediated resistance to fusidic acid in Staphylococcus aureus.

Molecular microbiology - 1 Jan 2006

O'Neill Alexander John, Chopra Ian

Abstract excerpt

The primary mechanism of fusidic acid resistance in clinical strains of Staphylococcus aureus involves acquisition of the fusB determinant. The genetic elements(s) responsible are incompletely defined, and the mechanism of resistance is unknown. Here we report the cloning, sequencing and overexpression of a single gene (fusB) from plasmid pUB101 capable of conferring resistance to fusidic acid in S. aureus. The...

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Identifiers

PMID: 16390458
DOI: 10.1111/j.1365-2958.2005.04971.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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