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HIV-1 Reverse Transcriptase: A Therapeutical Target in the Spotlight

30 Jan 2006

Abstract excerpt

Human Immunodeficiency Virus type 1 Reverse Transcriptase (HIV-1 RT) is one of the most important targets for treatment of Acquired Immune Deficiency Syndrome (AIDS). It catalyzes the reverse transcription of HIV-RNA into a double stranded DNA, and the knowledge of its substrate specificity and catalytic mechanism has guided the development of several inhibitors widely used on current HIV/AIDS therapy. However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16475939
DOI: 10.2174/092986706775476089

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