Article
Association of the DAT1 polymorphism with attention deficit hyperactivity disorder (ADHD): a family-based approach.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2006
Lim Myung-Ho, Kim Hyun Woo, Paik Ki-Chung, Cho Soo Churl, Yoon Do Young, Lee Heon-Jeong
Abstract excerpt
The dopamine transporter gene (DAT1) is of particular interest in the genetic study of attention deficit hyperactivity disorder (ADHD), because psychostimulants interact directly with the dopamine transporter protein. Association between ADHD and the 10-repeat allele of a 40 base pair (bp) variable number of tandem repeats (VNTR) polymorphism of DAT1 was first reported in 1995 [Cook et al. (1995); Am J Hum Genet...
Topics
- Alleles
- Attention Deficit Disorder with Hyperactivity
- Dopamine Plasma Membrane Transport Proteins
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Korea
- Linkage Disequilibrium
- Male
- Minisatellite Repeats
- Nuclear Family