Article
Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons.
FEBS letters - 23 Jan 2006
Miranda-Vizuete Antonio, Fierro González Juan Carlos, Gahmon Gabriele, Burghoorn Jan, Navas Plácido, Swoboda Peter
Abstract excerpt
Thioredoxins are a class of small proteins that play a key role in regulating many cellular redox processes. We report here the characterization of the first member of the thioredoxin family in metazoans that is mainly associated with neurons. The Caenorhabditis elegans gene B0228.5 encodes a thioredoxin (TRX-1) that is expressed in ASJ ciliated sensory neurons, and to some extent also in the posterior-most...
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