Article
No alcoholism-protection effects of ADH1B*2 allele in antisocial alcoholics among Han Chinese in Taiwan.
Alcoholism, clinical and experimental research - 1 Dec 2005
Lu Ru-Band, Ko Huei-Chen, Lee Jia-Fu, Lin Wei-Wen, Huang San-Yuan, Wang Tso-Jen, Wu Yi-Syuan, Lu Tsun-En, Chou Yuan-Hwa
Abstract excerpt
BACKGROUND: suggested that the genetic variation at ADH1B and ALDH2 influences the risk of alcoholism. The ADH1B*2 and ALDH2*2 alleles had been thought to be protective against alcoholism. Recent studies have suggested that either physiological tolerance of blood acetaldehyde, or innate insensitivity to it, or both may play a crucial role in keeping alcoholism from developing by protecting against adverse...
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