Article
MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder.
Alcoholism, clinical and experimental research - 1 Jun 2009
Lee Sheng-Yu, Hahn Cheng-Yi, Lee Jia-Fu, Chen Shiou-Lan, Chen Shih-Heng, Yeh Tzung Lieh, Kuo Po-Hsiu, Lee I Hui, Yang Yen Kuang, Huang San-Yuan, Ko Huei-Chen, Lu Ru-Band
Abstract excerpt
BACKGROUND: Antisocial alcoholism is related to dopamine and serotonin which are catalyzed by monoamine oxidase A (MAOA) and acetaldehyde dehydrogenase 2 (ALDH2). The objective of this study is to determine whether the interaction between the MAOA and the ALDH2 genes is associated with subjects with antisocial personality disorder (ASPD) having alcoholism. METHODS: A total of 294 Han Chinese men in Taiwan...
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