Article
First-line single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: a phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jan 2006
Niho Seiji, Kubota Kaoru, Goto Koichi, Yoh Kiyotaka, Ohmatsu Hironobu, Kakinuma Ryutaro, Saijo Nagahiro, Nishiwaki Yutaka
Abstract excerpt
PURPOSE: We conducted a phase II study of single agent treatment with gefitinib in chemotherapy-naïve patients with advanced non-small-cell lung cancer (NSCLC) to assess its efficacy and toxicity. PATIENTS AND METHODS: Patients received 250 mg doses of gefitinib daily. Administration of gefitinib was terminated if partial response (PR) was not achieved within 8 weeks or if tumor reduction was not observed within...
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