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Article

Adrenoleukodystrophy: new approaches to a neurodegenerative disease.

JAMA - 28 Dec 2005

Moser Hugo W, Raymond Gerald V, Dubey Prachi

Abstract excerpt

X-linked adrenoleukodystrophy (X-ALD), which was first described in 1923, was viewed until 1976 as a rare and inexorably fatal neurodegenerative disorder that affected boys. The genetic defect and biochemical abnormalities have now been defined. Ongoing research has resulted in new findings: (1) there is a wide range of phenotypic expression. At least half of patients with X-ALD are adults with somewhat milder...

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Identifiers

PMID: 16380594
DOI: 10.1001/jama.294.24.3131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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