Article
X linked adrenoleukodystrophy: clinical presentation, diagnosis, and therapy.
Journal of neurology, neurosurgery, and psychiatry - 1 Jul 1997
van Geel B M, Assies J, Wanders R J, Barth P G
Abstract excerpt
X linked adrenoleukodystrophy (X-ALD) is an inherited disorder of peroxisomal metabolism, biochemically characterised by accumulation of saturated very long chain fatty acids. Accumulation of these fatty acids is associated with cerebral demyelination, peripheral nerve abnormalities, and adrenoco...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Child
- Dietary Fats, Unsaturated
- Drug Combinations
- Erucic Acids
- Fatty Acids
- Female
- Genotype
- Humans
- Male
- Microbodies
- Peroxisomal Disorders
- Phenotype
- Prenatal Diagnosis
- Triolein