Article
Clinical course and endocrine dysfunction in X-linked adrenoleukodystrophy: A case series.
Endocrinologia, diabetes y nutricion - 1 Jan 2000
Matos Tânia, Costa Cristiana, Araújo Alexandra Novais, do Vale Sónia
Abstract excerpt
BACKGROUND AND PURPOSE: X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder affecting particularly the nervous tissue and adrenal cortex. Adrenomyeloneuropathy (AMN) is the most frequent phenotype, although adrenal insufficiency is usually the first manifestation in male patients. We set out to describe the clinical and biochemical features, together with the clinical course of X-ALD patients,...
Topics
- Male
- Humans
- Adrenoleukodystrophy
- Retrospective Studies
- Mineralocorticoids
- Phenotype
- Disease Progression