Article
Lack of association between the IL1A gene (-889) polymorphism and outcome after head injury.
Surgical neurology - 1 Jan 2006
Tanriverdi Taner, Uzan Mustafa, Sanus Galip Zihni, Baykara Onur, Is Merih, Ozkara Cigdem, Buyra Nur
Abstract excerpt
BACKGROUND: Interleukin (IL) 1 is a proinflammatory cytokine that has been identified as an important mediator of neurodegeneration induced by ischemia or traumatic brain injury. Accumulating evidence to date has suggested that the major cytokine contributing to neurodegeneration after head injury is IL-1beta rather than IL-1alpha; however, there is no sufficient data regarding IL-1alpha in literature, and there...
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